software
TreadScan
TreadScan is a component of our NeurodegenScan Suite and meets the needs for gait analysis of animals. Gait analysis allows highly sensitive, noninvasive detection and evaluation of many pathophysiological conditions, such as those occurring in Spinal Cord Injury, Parkinson’s disease, Alzheimer’s disease, ALS, arthritis, pain, neuromuscular and skeletal muscle diseases.
TreadScan system takes video of animal (mouse or rat) running on a transparent belt treadmill as input. The video of the ventral view (underside view) of the animal is obtained using a high‐speed digital camera and each video capture can be 20 seconds (or even more when used with specialized fast hard drive architecture) giving a multitude of stride samples in just one trial. The video essentially captures the foot prints of the animal as they walk/run on the treadmill. TreadScan software can work with videos taken from any treadmill that allows the capture of its footprints on any video capturing hardware system with a high‐speed camera.
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Features.
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Complete Gait Analysis software tool applicable on any treadmill providing clear ventral view
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Can be integrated with Side‐View Kinematic Gait Analysis with our KinemaScan upgrade
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Shows full animal body clearly at all times
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Operates in normal lighting environment of a lab
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Captures digital video at high‐speed (> 200 fps optional) for long durations only limited by storage
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Provides over 52 Different Measures of Gait!
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Automatically discards unusable portions of videos!
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Displays a Paw Pressure Map for each foot
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Features Incline and Decline capability for animal
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Stance measures can now be calculated for 3 distinct phases (Early‐, Mid‐ & Aft‐phase)
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ExerGait XL treadmill now has a ceiling light panel providing more uniform lighting
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Exports conveniently to Excel, formatted for input into Stats packages, as well as Group Export
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Lists raw data samples collected and totals stats
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Automatic Graphing of Gait Patterns in Export
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Software is trainable to adapt to changing environs
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Result review, Visualization of Acquired Experiments and Experiment Database Management
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Batch‐mode allows user to run multiple videos successively without human intervention
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Measures TreadScan can provide:
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Stride Time
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Stance & Swing
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Stride Length
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Paw Pressure
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Print Area
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Body‐Foot Spacing
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Foot‐Foot Spacing
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Running Speed
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Distance Walked
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Stance Graph
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Coupling/Coordination
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% of time # of feet on floor
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Print Length
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Toe Spread
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Intermediary Toe Spread
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Print Angle
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Gait Angle
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Body Rotation
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Body Shift
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Stride Frequency
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Applications:
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Spinal Cord Injury
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Parkinson’s Disease
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Alzheimer’s Disease
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ALS
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Arthritis
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Pain
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Neuromuscular Diseases
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Skeletal Muscle Diseases
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Ataxia
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Advanced Behavioral Insights
Clever Sys automates treadmill gait analysis to eliminate scoring bias and human error in preclinical trials. Our validated tracking technology provides high-resolution spatiotemporal metrics, enabling researchers to quantify motor deficits and therapeutic outcomes with superior sensitivity. By delivering instant, objective data, we streamline neuropharmacological screening and ensure robust data integrity for regulatory compliance in CNS research.
Tech Details
• Platform: Win 11/10
• Software: TreadScan (GaitScan Suite)
• Hardware: Customized Treadmill Apparatus
Publications(partial)
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Lee, D.E., McKay, L.K., Bareja, A. et al. Glutamine-driven reductive TCA cycle metabolism supports aged muscle stem cell function via de novo lipogenesis. Nat Aging 6, 1007–1020 (2026). https://doi.org/10.1038/s43587-026-01120-3.
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Silke Nuber, Xiaoqun Zhang, Thomas D. McCaffery, Tim E. Moors, Marie-Alexandre Adom, Wolf N. Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J. Selkoe. Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson’s disease phenotypes. Nature, Published: 29 February 2024. https://www.nature.com/articles/s41531-024-00662-w.
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Lisa S. Andersson, Martin Larhammar, Fatima Memic, Hanna Wootz, Doreen Schwochow, Carl-Johan Rubin, Kalicharan Patra, Thorvaldur Arnason, Lisbeth Wellbring, Göran Hjälm, Freyja Imsland, Jessica L. Petersen, Molly E. McCue, James R. Mickelson, Gus Cothran, Nadav Ahituv, Lars Roepstorff, Sofia Mikko, Anna Vallstedt, Gabriella Lindgren, Leif Andersson, Klas Kullander, (2012) Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice, Nature Volume: 488, Pages: 642–646 Date published: (30 August 2012) DOI: doi:10.1038/nature11399.
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Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.
Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.
Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.
Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.