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Automated Social Aggression Analysis

Our sophisticated software automates the Social Aggression paradigm, using video-based behavior recognition to quantify agonistic interactions. This ensures objective, high-throughput, and reproducible data for your laboratory.

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behavior PARADIGM/test

Social Aggression 

The Social Aggression test paradigm is a critical methodology in neuroscience for evaluating agonistic behavior and social hierarchy in animal models. By observing interactions such as dominance, defensive posturing, and physical confrontations, researchers gain insights into the neurobiological foundations of aggression and potential therapeutic interventions. Clever Sys transforms this paradigm by replacing traditional manual scoring with state-of-the-art, automated video-based behavior recognition. Our advanced computer vision algorithms categorize complex social cues in real-time, eliminating the subjective variability and fatigue inherent in human observation. This technology provides an objective framework for high-throughput data collection, ensuring that large-scale cohorts are analyzed with sub-second precision and unparalleled consistency. By integrating Clever Sys solutions, laboratories achieve the rigorous preclinical standards required for reproducible research and data integrity. Our streamlined approach empowers scientists to capture reliable behavioral phenotypes, facilitating more robust discoveries in central nervous system research and drug development workflows.

  • Typical Behavior Events

  • Fight

  • Aggressively Approach

  • Withdraw

  • Immobile

  • Explore

  • ................

  • Validated Precision:         Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.

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Traditional Methods

Manual Scoring

Observer Bias

Basic Insights

Time-Consuming 

Clever Sys AI

Fully Automated

Objective & Precise

Deep Data Analytics

Real-Time Analysis and Instant Results

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Advanced Behavioral Insights

Clever Sys’s Social Aggression solution automates video-based behavior recognition to eliminate scoring bias and human error in agonist research. By leveraging advanced vision algorithms, our technology delivers high-throughput analysis and precise quantification of social interactions. This fully automated approach enhances data reproducibility and accelerates drug discovery workflows by providing the rigorous evidence needed for preclinical compliance.

Tech Details

• Platform:       Win 11/10

• Software:     AggressionScan(TopScan with License for Corresponding Modules)

• Hardware:    Aggression Apparatus

Optimized Windows Software

Proven Academic Trust

Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.

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See high-fidelity AI-Powered Social Aggression Analysis in action: capturing behavior with sub-second precision to maintain rigorous preclinical standards.

Publications

  • Elizabeth A. Kleeman, Carolina Gubert, Sonali N. Reisinger, Kathryn C. Davidson, Da Lu, Merle Dayton, Liana Mackiewicz, Bethany A. Masson, Pranav Adithya, Alexandra L. Garnham,  Gemma Stathatos, Moira K. O ’ Bryan, Rikeish R. Muralitharan, Francine Z. Marques, Shanshan Li, Huan Liao, Shae McLaughlin, Emmet T. Keough, Michelle Y. Wheeler, Pamudika Kiridena, Marcel Doerflinger, Marc Pellegrini, Anthony J. Hannan. Paternal SARSCoV-2 infection impacts sperm small noncoding RNAs and increases anxiety in offspring in a sex-dependent manner. Nature Communications, volume 16, Article number: 9045 (2025) .
    https://www.nature.com/articles/s41467-025-64473-0#citeas.. 

  • Xu-Yi Li, Shi-Ya Zhang, Yi-Zhou Hong, Su Su Tang, tang_susu@126.com, Hao Wang, wanghao890625@126.com, Hao Hong, honghao@cpu.edu.cn. TGR5-mediated lateral hypothalamus-dCA3-dorsolateral septum circuit regulates depressive-like behavior in male
    mice.  Neuron, Volume 112, Issue 11p1795-1814.e10, June 05, 2024
    https://www.cell.com/neuron/fulltext/S0896-6273(24)00152-1.

  • Christine Ochoa Escamilla, Irina Filonova, Angela K. Walker, Zhong X. Xuan, Roopashri Holehonnur, Felipe Espinosa, Shunan Liu, Summer B. Thyme, Isabel A. López-García, Dorian B. Mendoza, Noriyoshi Usui, Jacob Ellegood, Amelia J. Eisch, Genevieve Konopka, Jason P. Lerch, Alexander F. Schier, Haley E. Speed & Craig M. Powell (2017) Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033

  • .....

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Precision Analytics

High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.

Instant Data Access

Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.

Preclinical Compliance

Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.

Seamless Integration

Modular architecture ensures interoperability with established lab infrastructure and data pipelines.

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