
behavior PARADIGM/test
Y-Maze/T-Maze/ Radial-Arm Maze
Y-maze, T-maze, and radial-arm maze paradigms are core tools for assessing spatial working memory, reference memory, and decision-making strategies. Subjects must navigate arms or branches to locate rewards or escape points, revealing alternation behavior, perseveration, and learning efficiency. Clever Sys automates these tasks with video-based Behavior Recognition, delivering precise tracking of arm entries, dwell time, and choice patterns across trials. Automated scoring removes observer bias, increases throughput, and provides rich, reproducible datasets ideal for preclinical studies in neurodegeneration, psychiatric disease, and cognitive enhancement.
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Automated Analytics:Â Advanced tracking and analysis removes subjective bias during analysis.
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Advanced Features:    Support various Event Sequence Measures (Combination, Alternation/Percentage, etc.) besides general metrics. Â
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Validated Precision:Â Â Â Â Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.



Traditional Methods


Manual Scoring

Observer Bias

Basic Insights
Time-ConsumingÂ
Clever Sys AI


Fully Automated

Object & Precise

Deep Data Analytics
Real-Time Analysis and Instant Results

Advanced Behavioral Insights
Clever Sys eliminates inter-observer variability by automating maze scoring with high-throughput precision. Our technology empowers researchers to quantify spatial memory and exploratory phenotypes with sub-second accuracy. By streamlining data acquisition, we provide high-reproducibility metrics that accelerate CNS drug discovery and ensure GLP-compliant results across global preclinical validation protocols for various paradigms.
Tech Details
• Platform:    Win 11/10
• Software:   TopScanLite/TopScan (with Corresponding LicenseÂ
• Hardware:  Maze Apparatus

Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
Publications
See high-fidelity AI-Powered Maze Analysis in action: capturing exploration with sub-second precision to maintain rigorous preclinical standards.
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Aron, L., Ngian, Z.K., Qiu, C. et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature 645, 712–721 (2025). https://doi.org/10.1038/s41586-025-09335-x.Â
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Tian Z, Song J, Zhao X, Zhou Y, Chen X, Le Q, Wang F, Ma L, Liu X. The interhemispheric amygdala-accumbens circuit encodes negative valence in mice. Science. 2024 Nov 8;386(6722):eadp7520. doi: 10.1126/science.adp7520. Epub 2024 Nov 8. PMID:39509508.
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Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-GarcÃa IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033.
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Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.

Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.

Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.

Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.
