behavior PARADIGM/test
Social Free InteractionÂ
The Social (Free) Interaction paradigm is a critical methodology for evaluating sociability, social novelty, and affiliate behaviors in preclinical neuroscience research. Clever Sys facilitates this complex assessment through our advanced, video-based behavior recognition technology, providing fully automated and high-throughput analysis of rodent interactions. By leveraging proprietary AI-driven algorithms, our system identifies specific social markers such as sniffing, following, and huddling with unmatched precision, ensuring that researchers can quantify subtle behavioral nuances without the variability of manual scoring. Our platform is engineered to meet the stringent demands of modern drug discovery and behavioral phenotyping, delivering objective, reproducible data in real time.
Â
Designed for seamless integration into existing lab workflows, the Clever Sys solution eliminates observer bias and provides a comprehensive suite of analytical tools to monitor social engagement across diverse experimental designs. From acute pharmacological studies to longitudinal genetic investigations, our automated video analysis empowers research teams with the defensible, high-resolution datasets necessary for significant scientific publication and regulatory-grade preclinical compliance.
-
Detected Behaviors.
-
Social Contact
-
Social Leave
-
Social Sniff
-
Contact By Body Part
-
​......
-
Social Approach
-
Social Follow
-
Social Distance
-
Body Part Distance
-
......
-
Validated Precision:Â Â Â Â Â Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.
Traditional Methods
Manual Scoring
Observer Bias
Basic Insights
Time-ConsumingÂ
Clever Sys AI
Fully Automated
Objective & Precise
Deep Data Analytics
Real-Time Analysis and Instant Results
Advanced Behavioral Insights
Clever Sys streamlines the Social Free Interaction paradigm by providing fully automated, video-based behavior recognition. Our high-resolution analysis eliminates the subjectivity of manual scoring, allowing neuroscience researchers to capture complex social dynamics with absolute precision. By integrating our proprietary AI patterns, labs can accelerate drug discovery and behavioral phenotyping while maintaining the highest standards for reproducible, preclinical research data.
Tech Details
• Platform:    Win 11/10
• Software:   SocialScan(TopScan with License for Corresponding Modules)
• Hardware:  Social Interaction Apparatus
Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
See high-fidelity AI-Powered Social Interaction Test Analysis (same color, similar size, one with mark) in action: capturing social behavior with sub-second precision to maintain rigorous preclinical standards.
Publications
-
Elizabeth A. Kleeman, Carolina Gubert, Sonali N. Reisinger, Kathryn C. Davidson, Da Lu, Merle Dayton, Liana Mackiewicz, Bethany A. Masson, Pranav Adithya, Alexandra L. Garnham, Gemma Stathatos, Moira K. O ’ Bryan, Rikeish R. Muralitharan, Francine Z. Marques, Shanshan Li, Huan Liao, Shae McLaughlin, Emmet T. Keough, Michelle Y. Wheeler, Pamudika Kiridena, Marcel Doerflinger, Marc Pellegrini, Anthony J. Hannan. Paternal SARSCoV-2 infection impacts sperm small noncoding RNAs and increases anxiety in offspring in a sex-dependent manner. Nature Communications, volume 16, Article number: 9045 (2025) .
https://www.nature.com/articles/s41467-025-64473-0#citeas.. -
Xu-Yi Li, Shi-Ya Zhang, Yi-Zhou Hong, Su Su Tang, tang_susu@126.com, Hao Wang, wanghao890625@126.com, Hao Hong, honghao@cpu.edu.cn. TGR5-mediated lateral hypothalamus-dCA3-dorsolateral septum circuit regulates depressive-like behavior in male
mice. Neuron, Volume 112, Issue 11p1795-1814.e10, June 05, 2024
https://www.cell.com/neuron/fulltext/S0896-6273(24)00152-1. -
Christine Ochoa Escamilla, Irina Filonova, Angela K. Walker, Zhong X. Xuan, Roopashri Holehonnur, Felipe Espinosa, Shunan Liu, Summer B. Thyme, Isabel A. López-GarcÃa, Dorian B. Mendoza, Noriyoshi Usui, Jacob Ellegood, Amelia J. Eisch, Genevieve Konopka, Jason P. Lerch, Alexander F. Schier, Haley E. Speed & Craig M. Powell (2017) Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033
-
.....
Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.
Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.
Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.
Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.