behavior PARADIGM/test
HomeCageScan: Circadian Rhythm AnalysisÂ
HomeCageScan delivers an advanced, unobtrusive system for round-the-clock behavioral tracking and circadian rhythm assessment within the rodent's primary residence. Leveraging sophisticated AI-driven video processing, the platform autonomously evaluates an extensive range of behaviors, facilitating a deeper understanding of daily activity patterns and physiological cycles. This automated approach removes observer interference and environmental stress, providing researchers with highly precise longitudinal data on sleep-wake fragmentation, phase shifts, and rhythm stability. In the fields of behavioral neuroscience and preclinical drug discovery, this tool enables the identification of minor phenotypic variations and therapeutic influences with superior sensitivity. Optimized for large-scale research environments, HomeCageScan generates objective, defensible results that align with strict regulatory expectations for data reliability and publication excellence. It serves as a vital resource for investigating chronobiological disruptions, metabolic dysfunction, and neurodegenerative conditions through a reliable, automated behavioral lens.
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Detected Behaviors.
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Rear Up
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Come Down
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Walk/Run
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Hang
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Jump
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Land
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Turn.
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Eat
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Drink
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Chew
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Sniff
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Dig
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Forage
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Circle
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Groom
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Stretch
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Sleep
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Twitch
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Pause
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Awaken
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Urinate
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Applications
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Disease Progression Studies
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Stereotypic Behavior Studies
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Genetic Research
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Toxicology Studies
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Foot/Liquid Intake Studies
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Obesity/Metabolism Studies
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Pain & Motor Deficiency
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Aging/Longitudinal Studies
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Validated Precision:Â Â Â Â Â Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.
Traditional Methods
Manual Scoring
Observer Bias
Basic Insights
Time-ConsumingÂ
Clever Sys AI
Fully Automated
Objective & Precise
Deep Data Analytics
Real-Time Analysis and Instant Results
Advanced Behavioral Insights
Automating circadian rhythm analysis via HomeCageScan eliminates human error and scoring variability in rodent studies. Neuroscience researchers utilize our AI to track longitudinal activity cycles and sleep patterns within the home cage. By analyzing continuous behavioral data, our platform produces the objective metrics necessary for rigorous preclinical research and efficient drug development in behavioral neuroscience.
Tech Details
• Platform:    Win 11/10
• Software:   HomeCageScan
• Hardware:  Customized HomeCageScan Environment/Apparatus
Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
See high-fidelity AI-Powered Home Cage Analysis in action: capturing exploration with sub-second precision to maintain rigorous preclinical standards.
Publications
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Li Y, Cacciottolo TM, Yin N, He Y, Liu H, Liu H, Yang Y, Henning E, Keogh JM, Lawler K, Mendes de Oliveira E, Gardner EJ, Kentistou KA, Laouris P, Bounds R, Ong KK, Perry JRB, Barroso I, Tu L, Bean JC, Yu M, Conde KM, Wang M, Ginnard O, Fang X, Tong L, Han J, Darwich T, Williams KW, Yang Y, Wang C, Joss S, Firth HV, Xu Y, Farooqi IS. Loss of transient receptor potential channel 5 causes obesity and postpartum depression. Cell. 2024 Aug 8;187(16):4176-4192.e17. doi: 10.1016/j.cell.2024.06.001. Epub 2024 Jul 2. PMID: 38959890; PMCID: PMC11961024.
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Wang QC, Zheng Q, Tan H, Zhang B, Li X, Yang Y, Yu J, Liu Y, Chai H, Wang X, Sun Z, Wang JQ, Zhu S, Wang F, Yang M, Guo C, Wang H, Zheng Q, Li Y, Chen Q, Zhou A, Tang TS (2016) . TMCO1 Is an ER Ca(2+) Load-Activated Ca(2+) Channel, Cell. 2016 Jun 2;165(6):1454-66. doi: 10.1016/j.cell.2016.04.051. Epub 2016 May 19.
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Dietrich MO, Zimmer MR, Bober J, Horvath TL. Hypothalamic Agrp neurons drive stereotypic behaviors beyond feeding. Cell. 2015 Mar 12;160(6):1222-32. doi: 10.1016/j.cell.2015.02.024. Epub 2015 Mar 5. Erratum in: Cell. 2017 Apr 20;169(3):559. doi: 10.1016/j.cell.2017.04.006. PMID: 25748653; PMCID: PMC4484787.
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Hua Y, Sahashi K, Rigo F, Hung G, Horev G, Bennett CF, Krainer AR (2011) , Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model, Nature. 2011 Oct 5;478(7367):123-6. doi: 10.1038/nature10485
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Chen, D., Steele, A. D., Lindquist, S., & Guarente, L. (2005). Increase in activity during calorie restriction requires Sirt1. Science, 310(5754), 1641
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Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.
Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.
Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.
Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.