behavior PARADIGM/test
Water Maze Test
The Morris water maze is a gold-standard paradigm for assessing spatial learning and memory. Subjects must locate a hidden platform in a circular pool using distal visual cues, allowing precise measurement of acquisition, retention, and flexibility of spatial navigation. Latency, path length, swim speed, and search strategies are quantified across training and probe trials. This task is highly sensitive to hippocampal function, pharmacological manipulation, and genetic models, making it ideal for preclinical research in neurodegeneration, psychiatric disease, and cognitive enhancement.
Clever Sys transforms traditional Morris water maze testing into a fully automated, high-throughput solution. Our video-based Behavior Recognition technology tracks each subject’s swim path in real time, quantifying latency, distance, quadrant preference, and search strategies with frame-level precision. Automated scoring eliminates observer bias, reduces labor, and ensures consistent, reproducible data across cohorts and studies. Integrated visualization and export tools streamline analysis and reporting, helping your lab accelerate discovery while maintaining rigorous scientific standards in spatial learning and memory research.
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Automated Analytics:Â Advanced tracking and analysis removes subjective bias during water maze analysis.
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Advanced Features:    Support extended metrics including Whishaw’s Corridor as well as Turning Event/Ratio etc., besides general water maze metrics, Â
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Validated Precision:Â Â Â Â Â Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.
Traditional Methods
Manual Scoring
Observer Bias
Basic Insights
Time-ConsumingÂ
Clever Sys AI
Fully Automated
Objective & Precise
Deep Data Analytics
Real-Time Analysis and Instant Results
Advanced Behavioral Insights
Clever Sys automates spatial learning assays to eliminate inter-observer variability and manual scoring errors. High-throughput automation allows researchers to quantify cognitive drivers and navigational strategies with unparalleled precision. By delivering instant, objective data, our platform ensures high-fidelity results for rigorous preclinical compliance and accelerates CNS drug development through standardized behavioral phenotypes.
Tech Details
• Platform:    Win 11/10
• Software:   WaterMazeScan/TopScanLite/TopScan (with Corresponding License )
• Hardware:  Water Maze Apparatus
Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
Publications
See high-fidelity AI-Powered Water Maze Analysis in action: capturing behavior and data with sub-second precision to maintain rigorous preclinical standards.
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Aron, L., Ngian, Z.K., Qiu, C. et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature 645, 712–721 (2025). https://doi.org/10.1038/s41586-025-09335-x.Â
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Tian Z, Song J, Zhao X, Zhou Y, Chen X, Le Q, Wang F, Ma L, Liu X. The interhemispheric amygdala-accumbens circuit encodes negative valence in mice. Science. 2024 Nov 8;386(6722):eadp7520. doi: 10.1126/science.adp7520. Epub 2024 Nov 8. PMID:39509508.
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Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-GarcÃa IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033.
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Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.
Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.
Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.
Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.