
behavior PARADIGM/test
Stereotypic: Grooming
/Rearing
Quantifying stereotypic behaviors like grooming and rearing is essential for characterizing phenotypic shifts in neuropsychiatric and neurodegenerative rodent models. These actions provide critical insights into anxiety levels, repetitive drive, and motor function. Traditional assessment of such behaviors relies on manual observation, which is inherently prone to subjectivity, human error, and low scalability. Subtle sequences of face washes, paw licks, and postural rearing frequencies are often missed, compromising the sensitivity of behavioral assays in pharmacological or genetic studies.Clever Sys addresses these challenges with specialized video-based recognition software that automates the detection of grooming strings and rearing events with frame-by-frame accuracy. By utilizing advanced computer vision, our technology differentiates between micro-grooming and full-body sequences, while precisely logging the duration and frequency of unsupported and supported rearing. This high-throughput capability ensures maximum objectivity and rigorous preclinical compliance for your research. Our platform transforms raw video data into robust, publication-ready metrics, enabling scientists to detect the therapeutic impact of compounds on stereotypic expressions with unparalleled detail.
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Automated Analytics:Â Â Advanced Grooming and Rearing detection algorithm removes subjective bias.
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Advanced Features:Â Â Â Â Â Â Â Â Accurate Grooming and Rearing Detection and Judging.Â
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Validated Precision:Â Â Â Â Â Â Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.


Traditional Methods


Manual Scoring

Observer Bias

Basic Insights
Time-ConsumingÂ
Clever Sys AI


Fully Automated

Objective & Precise

Deep Data Analytics
Real-Time Analysis and Instant Results

Advanced Behavioral Insights
By digitizing stereotypic behavior assessment, Clever Sys eliminates the subjectivity inherent in manual grooming and rearing logs. Our specialized AI distinguishes micro-grooming from complex sequences with frame-by-frame precision, providing researchers with reliable phenotypic biomarkers. This automated approach accelerates drug discovery workflows by delivering high-throughput, objective data that meets the most rigorous preclinical standards.
Tech Details
• Platform:    Win 11/10
• Software:   TopScan (with License for Corresponding Modules)
• Hardware:  Test Apparatus

Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
Publications
See high-fidelity AI-Powered Grooming Analysis in action: capturing exploration with sub-second precision to maintain rigorous preclinical standards.
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Aron, L., Ngian, Z.K., Qiu, C. et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature 645, 712–721 (2025). https://doi.org/10.1038/s41586-025-09335-x.Â
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Tian Z, Song J, Zhao X, Zhou Y, Chen X, Le Q, Wang F, Ma L, Liu X. The interhemispheric amygdala-accumbens circuit encodes negative valence in mice. Science. 2024 Nov 8;386(6722):eadp7520. doi: 10.1126/science.adp7520. Epub 2024 Nov 8. PMID:39509508.
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Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-GarcÃa IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033.
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Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.

Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.

Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.

Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.
