behavior PARADIGM/test
Open Field Test
The Open Field Test is a foundational behavioral paradigm for assessing locomotor activity, exploration, and anxiety-like behavior in rodents. Animals are placed in a novel arena, and their spontaneous movement patterns, zone preferences, and exploratory behaviors are monitored over time. Subtle changes in these measures can reflect anxiety, habituation, or the impact of pharmacological or genetic manipulations.
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Clever Sys’s automated Open Field solution uses high‑resolution video tracking and AI-based behavior recognition to capture detailed paths, zone entries, rearing, immobility, and time spent in center vs. periphery. This fully automated workflow removes observer bias, increases throughput, and delivers reproducible, publication-ready data. Integrated analytics help preclinical teams rapidly quantify treatment effects and compare cohorts with confidence.
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Automated Analytics:Â Advanced tracking algorithm removes subjective bias during Open Field test.
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Advanced Features: Support Extended Events such as Distance-To-Point, , Distance-To-Area, Orientation-To-Point etc. and related metrics.
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Related Research:     Locomotor, Anxiety, Pain related, etc.Â
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Validated Precision:Â Â Â Â Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.
Traditional Methods
Manual Scoring
Observer Bias
Basic Insights
Time-ConsumingÂ
Clever Sys AI
Fully Automated
Objective & Precise
Deep Data Analytics
Real-Time Analysis and Instant Results
Advanced Behavioral Insights
Our automated Open Field analytics eliminate variability and inter-rater bias, delivering standardized metrics for locomotor and anxiety profiling. By providing real-time data on complex exploratory patterns, our technology accelerates CNS phenotyping and drug efficacy screenings. This highly scalable platform ensures full preclinical compliance and provides the robust, quantitative evidence essential for high-impact peer-reviewed publications.
Tech Details
• Platform:    Win 11/10
• Software:   TopScan
• Hardware:  Open Field Apparatus
Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
Publications
See high-fidelity AI-Powered Open-Field Test Analysis in action: capturing exploration with sub-second precision to maintain rigorous preclinical standards.
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Aron, L., Ngian, Z.K., Qiu, C. et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature 645, 712–721 (2025). https://doi.org/10.1038/s41586-025-09335-x.Â
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Tian Z, Song J, Zhao X, Zhou Y, Chen X, Le Q, Wang F, Ma L, Liu X. The interhemispheric amygdala-accumbens circuit encodes negative valence in mice. Science. 2024 Nov 8;386(6722):eadp7520. doi: 10.1126/science.adp7520. Epub 2024 Nov 8. PMID:39509508.
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Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-GarcÃa IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033.
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Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.
Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.
Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.
Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.