
behavior PARADIGM/test
Drug Effect/ Cocaine on Rat
Behavioral evaluation of cocaine in lab models is a standard neuroscience technique to study the stimulant and reinforcing effects of narcotics. Cocaine triggers varied dose-related responses, such as faster movement, fixed motor patterns, and unique exploration habits. Among these, physical activation, head-waving, and darting are often vital markers of drug-triggered changes in motor control and brain activity. These profiles offer glimpses into the neural pathways of stimulant drugs and are used often in research on addiction and dopamine levels.Â
Clever Sys offers a sophisticated automated DrugEffectScan that leverages high-speed video acquisition and advanced computer vision to quantify drug related behaviors. This high-throughput solution eliminates the variability associated with manual observation, ensuring objective data collection and rigorous preclinical compliance. By automating detection of Head Waving, Darting, and Locomotor/In-Place/Immobile, our platform empowers researchers to generate reproducible, publication-quality insights into treatment efficacy and neuroprotection.
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Automated Analytics: AI-powered Behavior Analyzing algorithm removes subjective bias.
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Advanced Features:Â Â Â Â Accurate Detection of Head Waving, Darting, and Locomotor /In-Place/Immobile Activity.Â
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Validated Precision:Â Â Â Â Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.


Traditional Methods


Manual Scoring

Observer Bias

Basic Insights
Time-ConsumingÂ
Clever Sys AI


Fully Automated

Objective & Precise

Deep Data Analytics
Real-Time Analysis and Instant Results

Advanced Behavioral Insights
Our DrugEffectScan platform utilizes high-resolution video tracking to provide neuroscientists with a robust, automated solution for quantifying drug-induced changes. By precisely measuring shifts in locomotion, posture, and exploratory actions over time, it eliminates observer subjectivity. This advanced technology produces the sensitive, reproducible, and publication-ready data required for rigorous pharmacological research and drug discovery.
Tech Details
• Platform:    Win 11/10
• Software:   DrugEffectScan (TopScan with License for Corresponding Modules)
• Hardware:  Testing Apparatus

Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
Publications
See high-fidelity AI-Powered Drug Effect Analysis in action: capturing exploration with sub-second precision to maintain rigorous preclinical standards.
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Aron, L., Ngian, Z.K., Qiu, C. et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature 645, 712–721 (2025). https://doi.org/10.1038/s41586-025-09335-x.Â
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Tian Z, Song J, Zhao X, Zhou Y, Chen X, Le Q, Wang F, Ma L, Liu X. The interhemispheric amygdala-accumbens circuit encodes negative valence in mice. Science. 2024 Nov 8;386(6722):eadp7520. doi: 10.1126/science.adp7520. Epub 2024 Nov 8. PMID:39509508.
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Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-GarcÃa IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033.
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Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.

Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.

Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.

Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.
