behavior PARADIGM/test
Social Dominance /Tube TestÂ
The Social Dominance or Tube Test is a classical behavioral paradigm used by neuroscience researchers to evaluate social hierarchy and dominance interactions within a competitive environment. Traditionally, this test involves two subjects released into opposite ends of a narrow tube, where the dominant individual forces the subordinate to retreat. Measuring these social interactions has historically relied on manual scoring, which is prone to observer fatigue and variability. Clever Sys revolutionizes this assessment by providing fully automated, video-based behavior recognition and analysis. Our advanced software detects subtle contact cues and movement patterns with precision, facilitating objective, high-throughput, and reproducible data collection across large cohorts. By eliminating manual subjectivity, Clever Sys enables labs to generate stable, verifiable results that are essential for studying the neural mechanisms of social behavior and developing novel central nervous system therapeutics. Our system ensures that every trial follows rigorous preclinical standards for maximum data integrity.
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Typical Behavior Events
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TubeTest Location:Â Animal 1 in Specific Area
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TubeTest Location:Â Animal 2 in Specific Area
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Both Animals Stay in Specific Area at same time
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Animal 1 and 2 Contact in Specific Area
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Push
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Resist
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Push Back
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Retreat
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Validated Precision:Â Â Â Â Â Used by top scientists to meet preclinical compliance and produce robust, verifiable research data.
Traditional Methods
Manual Scoring
Observer Bias
Basic Insights
Time-ConsumingÂ
Clever Sys AI
Fully Automated
Objective & Precise
Deep Data Analytics
Real-Time Analysis and Instant Results
Advanced Behavioral Insights
Clever Sys automates the Social Dominance Tube Test by utilizing advanced video-based recognition to eliminate manual scoring variability. Our platform provides neuroscience researchers with unparalleled accuracy and high-throughput capabilities by detecting subtle interactions in real-time. This objective analysis ensures total reproducibility across large study cohorts, delivering the rigorous data integrity required for modern drug development and CNS research.
Tech Details
• Platform:    Win 11/10
• Software:   TopScan
• Hardware:  TubeTest Apparatus
Optimized Windows Software
Proven Academic Trust
Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.
Publications
See high-fidelity AI-Powered Tube Test Analysis in action: capturing exploration with sub-second precision to maintain rigorous preclinical standards.
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Elizabeth A. Kleeman, Carolina Gubert, Sonali N. Reisinger, Kathryn C. Davidson, Da Lu, Merle Dayton, Liana Mackiewicz, Bethany A. Masson, Pranav Adithya, Alexandra L. Garnham, Gemma Stathatos, Moira K. O ’ Bryan, Rikeish R. Muralitharan, Francine Z. Marques, Shanshan Li, Huan Liao, Shae McLaughlin, Emmet T. Keough, Michelle Y. Wheeler, Pamudika Kiridena, Marcel Doerflinger, Marc Pellegrini, Anthony J. Hannan. Paternal SARSCoV-2 infection impacts sperm small noncoding RNAs and increases anxiety in offspring in a sex-dependent manner. Nature Communications, volume 16, Article number: 9045 (2025) .
https://www.nature.com/articles/s41467-025-64473-0#citeas.. -
Xu-Yi Li, Shi-Ya Zhang, Yi-Zhou Hong, Su Su Tang, tang_susu@126.com, Hao Wang, wanghao890625@126.com, Hao Hong, honghao@cpu.edu.cn. TGR5-mediated lateral hypothalamus-dCA3-dorsolateral septum circuit regulates depressive-like behavior in male
mice. Neuron, Volume 112, Issue 11p1795-1814.e10, June 05, 2024
https://www.cell.com/neuron/fulltext/S0896-6273(24)00152-1. -
Christine Ochoa Escamilla, Irina Filonova, Angela K. Walker, Zhong X. Xuan, Roopashri Holehonnur, Felipe Espinosa, Shunan Liu, Summer B. Thyme, Isabel A. López-GarcÃa, Dorian B. Mendoza, Noriyoshi Usui, Jacob Ellegood, Amelia J. Eisch, Genevieve Konopka, Jason P. Lerch, Alexander F. Schier, Haley E. Speed & Craig M. Powell (2017) Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033
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Precision Analytics
High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.
Instant Data Access
Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.
Preclinical Compliance
Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.
Seamless Integration
Modular architecture ensures interoperability with established lab infrastructure and data pipelines.