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Barnes Maze Test: Spatial Learning and Memory Assay

Accurately measure escape latency, path length, and hole choice behavior in rodents with automated tracking designed for high-resolution spatial navigation studies.

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Barnes Maze Test

The Barnes Maze system serves as a premier instrument for neuroscience researchers investigating spatial learning and memory. By integrating advanced automated video-based analysis, our platform eliminates manual scoring errors, ensuring unparalleled accuracy and reproducibility across all behavioral trials.

 

This dry-land navigational assay provides a high-throughput solution that minimizes subject stress, delivering objective data essential for modern preclinical drug discovery. Through sophisticated tracking technology, researchers can precisely quantify escape latencies and hole-search strategies with ease. Clever Sys provides the engineering excellence required to transform behavioral observations into high-impact scientific insights, supporting the development of novel therapeutic interventions.

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Traditional Methods

Manual Scoring

Observer Bias

Basic Insights

Time-Consuming 

Clever Sys AI

Fully Automated

Objective & Precise

Deep Data Analytics

Real-Time Analysis and Instant Results

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Advanced Behavioral Insights

Clever Sys automates behavioral assays to eliminate inter-observer variability and manual scoring bias. Our advanced software allows neuroscientists to quantify spatial learning and memory biomarkers with unprecedented throughput. By streamlining high-resolution data acquisition, the platform provides the validated, objective metrics necessary for GLP-compliant preclinical trials and efficient CNS drug discovery pipelines.

Tech Details

• Platform:       Win 11/10

• Software:     TopScan

• Hardware:    Barnes Maze Apparatus

Optimized Windows Software

Proven Academic Trust

Our technology represents the industry benchmark for automated behavior testing. Scientific teams across the globe have published findings based on Clever Sys tech, adhering to strict preclinical compliance protocols while ensuring the highest level of data integrity and objectivity within prestigious international journals.

See high-fidelity AI-Powered Maze Analysis in action: capturing exploration with sub-second precision to maintain rigorous preclinical standards.

Publications

  • Aron, L., Ngian, Z.K., Qiu, C. et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature 645, 712–721 (2025). https://doi.org/10.1038/s41586-025-09335-x. 

  • Tian Z, Song J, Zhao X, Zhou Y, Chen X, Le Q, Wang F, Ma L, Liu X. The interhemispheric amygdala-accumbens circuit encodes negative valence in mice. Science. 2024 Nov 8;386(6722):eadp7520. doi: 10.1126/science.adp7520. Epub 2024 Nov 8. PMID:39509508.

  • Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-García IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231. doi: 10.1038/nature24470. Epub 2017 Nov 1. PMID: 29088697; PMCID: PMC5787033.

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Precision Analytics

High-resolution tracking engines delivering granular spatial data for complex behavioral phenotyping.

Instant Data Access

Dynamic processing enables immediate visualization and rapid validation of experimental trial flows.

Preclinical Compliance

Engineered to satisfy rigorous regulatory mandates for reproducible and valid preclinical research.

Seamless Integration

Modular architecture ensures interoperability with established lab infrastructure and data pipelines.

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