The LadderScan Test Apparatus consists of a horizontal ladder in between two shelter boxes. Each shelter boxes are equipped with automatic doors, tones, fans and shockers. All these stimuli are used as cues for departure. They control the speed of the mice and to prevent them from leaving the shelter box at the opposite side and crossing the ladder at unwanted moments. 
Two automatic doors are installed at both ends of the ladder which controls animal’s walking in and out. Two small enclosures are used at both ends to make animal comfortable to walk to the end. which are equipped with a bright white LED spotlight in the roof and two pressurized air outlets High pitch tone and Both, light and air stimuli are used as cues for departure. In addition, one of the air outlets is used to control the speed of the mice and to prevent them from leaving the shelter box at the opposite side and crossing the ladder at unwanted moments (which we call ‘escape’).
The ladder has 2 × 37 rungs for the left and right side. All rungs are touch sensitive sensors,, which are continuously monitored and which can be used to register and analyze the walking pattern of the mouse instantaneously. Moreover, based upon the prediction of the walking pattern, the rungs can be moved up or down by a novel device. The computer system (runs the real-time system recording sensor data, adjusts air pressure, predicts future touches, calculates interventions, repositions slides and stores data, operates in a fixed cycle of 2.